AK2 (Adenylate Kinase2, 1-239aa, His-tagged), Human

pDESCRIPTION: Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.br /
Synonyms: ADK2br /
AA Sequence:br /
MGSSHHHHHH SSGLVPRGSH MAPSVPAAEP EYPKGIRAVL LGPPGAGKGTbr /
QAPRLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVVbr /
ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE KLDSVIEFSIbr /
PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNEbr /
KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKAbr /
TCKDLVMFI/p
pnbsp;/p
pnbsp;/p
pSOURCE: Recombinant, ,E.coli expression systembr /
MOLECULAR WEIGHT: 28.6 kDa (259 aa)br /
PURITY: gt; 95% by SDS PAGEbr /
FORM: Purified, in 20mM Tris pH 7.5, 5mM DTT, 20% glycerolbr /
ENDOTOXIN: lt; 1.0 EU per 1㎍ of protein (determined by LAL method)br /
CONCENTRATION: 1 mg/ml (Bradford Assay)br /
STORAGE: -20deg;C (aliquot), Avoid repeated freeze and thaw cycles/p