Adenylate Kinase 3, human

貨號 Cat. No.
01-2101
規格 Size
25 μg
品牌 Brand
ARP

Description

pbr /
DESCRIPTION: Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Five isozymes of adenylate kinase have been identified in vertebrates. AK1 is present in the cytosol of skeletal muscle, brain, and erythrocyte, while AK2 is localized in the intermembrane space of mitochondria of liver, kidney, spleen and heart. AK3, called GTP:AMP phosphotransferase, exists in the mitochondrial matrix of liver and heart. These isozymes contribute to homeostasis of the adenine nucleotide composition in the cell.br /
Synonyms: AK3, AKL3L, Adenylate kinase 3 alpha like 1br /
AA Sequence:br /
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASK LLRAVILGPP GSGKGTVSQR IAQNFGLQHL SSGHFLRENI KASTEVGEMA KQYIEKSLLV PDHVITRLMMbr /
SELENRRGQH WLLDGFPRTL GQAEALDKIC EVDLVISLNI PFETLKDRLS RRWIHPPSGR VYNLDFNPPH VHGIDDVTGE PLVQQEDDKP EAVAARLRQY KDVAKPVIEL YKSRGVLHQFbr /
SGTETNKIWP YVYTLFSNKI TPIQSKEAYbr /
SOURCE: Recombinant, His-tagged, E. coli expression systembr /
MOLECULAR WEIGHT: 29.3 kDa (259 aa)br /
PURITY: gt; 90% (SDS PAGE)br /
FORM: Purified, in 20mM Tris-HCl, pH 8, 2mMDTT, 20% Glycerolbr /
CONCENTRATION: 1 mg/mlbr /
STORAGE: -20deg;C (aliquot), Avoid repeated freeze and thaw cycles/p

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