Villin Antibody (clone CWWB1)

 Mouse monoclonal antibody suitable for immunohistochemistry and western blotting.



Functional Aspects:

Villin is found predominantly in epithelial cells that develop a brush border such as those in the intestinal mucosa, gall bladder, kidney proximal tubules, and ductuli efferentes of the testis. It is located in the apical cytoplasm, adjacent to the villus, and hence is a good indicator of cell polarity. This protein is composed of three domains. The first two domains are homologous and the third domain is called the headpiece. This antibody was generated using a recombinant protein corresponding to the C-terminal “headpiece” region of the human villin molecule.