Unconjugated Galanthus Nivalis Lectin (GNL)

metalloprotein and does not require Ca⁺⁺ or Mn⁺⁺ for binding.



Binding seems to be preferentially directed toward structures containing (α-1,3) mannose residues. Also in contrast to most mannose-binding lectins, GNL will not bind α-linked glucose. Reports indicate that this lectin binds rat and mouse IgM but not IgG. The only protein from human serum reported to bind to this lectin is α2-macroglobulin. GNL binds to many viral glycoproteins.



Inhibiting/Eluting Sugar: 100 mM - 200 mM α-methylmannoside