ret Oncoprotein Antibody (clone 3F8)

Mouse monoclonal antibody suitable for immunohistochemistry.



Functional Aspects:

Ret expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuroretina, and the growing tips of the renal collecting ducts in developing kidney. Mutations of the ret proto-oncogene are implicated in certain developmental abnormalities and tumors. This antibody was raised to the intracellular domain of the molecule, present in all isoforms of the protein.