Placental Alkaline Phosphatase Antibody (rabbit monoclonal)

Rabbit monoclonal antibody suitable for use on formalin-fixed, paraffin embedded tissue sections using standard immunohistochemistry methods.



Functional Aspects:

Placental alkaline phosphatase (PLAP) is only found in normal term placenta, endocervix, and oviduct and in ovarian and proximal intestinal tumors. A PLAP-like variant is seen mostly in fetal testis and thymus and some defined tumors. Clone 8A9 stains seminomas and placenta indicating a specificity for both PLAP and PLAP-like enzyme. Clone SP15 reacts with a membrane-bound isoenzyme of PLAP occurring in the placenta during the 3rd trimester of gestation.