Parvalbumin Antibody (Alpha; clone 2E11)

Mouse monoclonal antibody suitable for immunohistochemistry.



Functional Aspects:

Alpha and beta parvalbumins are expressed in different human tissues with the alpha form highly expressed in extracts of human cerebellum, weakly in kidney and not in skeletal muscle, thymus, lung, placenta, heart, liver, and diaphragm. Reduced expression of alpha parvalbumin has been reported in Purkinje cells in cases of spinocerebellar ataxia-1. This antibody does not detect parvalbumin in preterm placenta thereby indicating its specificity for the alpha form of this protein.