M2A Antigen Antibody (Lymphatic Endothelial Cell Marker; clone D2-40)

Mouse monoclonal antibody suitable for immunohistochemistry on human paraffin embedded, formalin-fixed tissue.



Functional Aspects:

This antibody recognizes the M2A oncofetal antigen, a 40 kDa, O-linked sialoglycoprotein, expressed on the cell membrane of lymphatic endothelium, fetal gonocytes, and certain germ cell tumor cell lines. No reactivity is seen on cancer cell lines of human breast, prostate, melanoma, cervix, colon, pharynx, brain, and bone marrow. This antibody has also been shown to be a useful marker for cells of mesothelial origin, including malignant mesothelioma.