Estrogen Receptor (beta) Antibody (clone EMR02)

Mouse monoclonal antibody suitable for immunohistochemistry and western blotting.



Functional Aspects:

Estrogen receptor (ER) is expressed in a variety of different tissues but is found most prominently in the female reproductive tract. A large amount of research has focused on the differential expression of ER in human breast cancer. Clone 6F11 was raised against a prokaryotic recombinant protein corresponding to the full-length alpha form of the human ER molecule. Clone EMR02 is directed to the wild type C-terminus of human ER beta. Clone 1D5 reacts specifically with ER alpha and shows no reaction with ER beta. Clone SP1 is a rabbit monoclonal antibody generated from a synthetic peptide derived from the C-terminus of human ER alpha molecule.