Cyclin D1 Antibody (rabbit monoclonal)

Rabbit monoclonal antibody suitable for use on formalin-fixed, paraffin embedded tissue sections using standard immunohistochemistry methods.



Functional Aspects:

Maximum expression of cyclin D1 occurs at a critical point in mid to late G1 phase of the cell cycle. Cyclin D1 expression has been shown to be amplified in tumors such as breast cancer and mantle cell lymphoma. Clones DCS-6 and P2D11F11 were both raised against full-length cyclin D1 and SP4 was raised against the C-terminus of cyclin D1.