COX-2 Antibody (rabbit monoclonal)

Rabbit monoclonal antibody suitable for use on formalin-fixed, paraffin embedded tissue sections using standard immunohistochemistry methods.



Functional Aspects:

Cyclooxygenase-2 is found in normal skin and epithelial cells of various diseases and cancers. In Crohn’s disease and ulcerative colitis, cyclooxygenase-2 is strongly expressed in the upper crypts, surface epithelial cells, and in the mononuclear cells of the lamina propria. It is expressed in both epithelial and interstitial cells of adenomatous polyps and several adenocarcinomas as well as in a high proportion of esophageal squamous cell carcinomas. Clone SP21 was raised against the C-terminus of rat Cox-2.