Choline Acetyltransferase Antibody (clone 38B12)

Mouse monoclonal antibodies suitable for immunohistochemistry.



Functional Aspects:

Choline Acetyltransferase (ChAT) is found in cholinergic neurons in the CNS. Specific loss of cholinergic neurons has been reported in the basal forebrain in Lewy body dementia and Alzheimer’s disease. It does not react with axons in the insular cortex or the internal capsule, non-cholinergic structures, endothelial cells, or microglia. Clone 38B12 was raised against the C-terminus of ChAT.