CD146 Antibody (MCAM; clone N1238)

Mouse monoclonal antibody suitable for immunohistochemistry and western blotting.



Functional Aspects:

Originally, the CD146 molecule was defined as a marker of tumor progression and metastasis formation in human melanoma. CD146 can be induced on some T cells. More recently, it has been reported to be expressed on endothelial cells, smooth muscle and cerebellar cortex. Clone N1238 was raised against the extracellular domain of CD146.