SinoBiological | 肥胖 (Obesity) 與糖尿病 (Diabetes) 的關鍵標的：GLP-1R, GIPR, 和 GCGR

GLP-1R, GIPR, and GCGR are key targets for diabetes and obesity treatment. GLP-1R enhances insulin secretion and satiety, while GIPR and GCGR regulate glucose and energy balance. Therapeutics like GLP-1R agonists (e.g., semaglutide), dual agonists (e.g., tirzepatide), and triple agonists (e.g., retatrutide) have shown promise in treating metabolic disorders. Sino Biological’s recombinant GLP-1R, GIPR, and GCGR proteins provide essential tools in this area of research.

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Featured Products from Sino Biological


Validated activity	Broad coverage of tags	Highly cited in reputable journals

	Human GCGR recombinant-proteins
	HPLC-verified (Cat#: 30122-H08H)
	ELISA. Binding of human anti-GCGR (Volagidemab) to recombinant human GCGR protein.

	Human GLP-1R Protein
	Nanodisc (Cat#: 13944-H88H-NA)
	ELISA. Binding of Human GLP1R-Nanodisc Protein to Anti-GLP1R mAb.

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This poster features the physiologic roles of GLP-1R, GIPR, and GCGR, as well as their potential as therapeutic targets for diabetes and obesity. In addition, research applications and drug development targeting these targets are discussed.

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