Z-Leu-Leu-Leu-B(OH)2 (MG-262)
- 貨號 Cat. No.
- I-120
- 規格 Size
- 200 μg
- 品牌 Brand
- Boston Biochem
Description
Z-Leu-Leu-Leu-B(OH)2 (MG-262)
Synthetic
Product Information
200 μg
95% by HPLC. Structure confirmed by 1H-NMR.
Soluble and stable in DMSO up to 15 mg/ml.
Ki = 0.023 nM vs. SDS-activated 20S Proteasome.
Use & Storage
Highly potent and selective cell-permeable inhibitor of the proteasome.
Store at -20°C. Avoid multiple freeze/thaw cycles.
Catalog #: I-120
Z-Leu-Leu-Leu-B(OH)2 (MG-262)
Product Source:
Synthetic
This peptide boronic acid is structurally similar to the peptide aldehyde MG-132 and also inhibits the chymotrypsin-like peptidase activity of the proteasome, but with much higher potency. These inhibitors are reversible and cell-permeable, and also inhibit the activity of calpains and cathepsins.
Product Information
Quantity:
200 μg
Structure:
Purity:
95% by HPLC. Structure confirmed by 1H-NMR.
Solubility:
Soluble and stable in DMSO up to 15 mg/ml.
Activity:
Ki = 0.023 nM vs. SDS-activated 20S Proteasome.
Use & Storage
Use:
Highly potent and selective cell-permeable inhibitor of the proteasome.
Storage:
Store at -20°C. Avoid multiple freeze/thaw cycles.