Z-IETD-FMK

STORAGE: Store at –20^oC.

SHELF LIFE: 1 year under proper storage conditions

MOLECULAR WEIGHT: 654.0

SEQUENCE: Z-ILe-Glu(OMe)-Thr-Asp(OME)-FMK

PURITY: One spot by TLC

PACKAGE CONTENTS: Z-IETD-FMK in lyophilized powder

RECONSTITUTION: Reconstitute in DMSO (20 mM)

DESCRIPTION:

A synthetic peptide that irreversibly inhibits activity of IETD-dependent caspases (e.g., caspase-8). The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies.

RECOMMENDED USAGE:

We recommend using 2-10 ìM for inhibiting caspase activity in cell culture. The optimal doses may vary among different cells and culture conditions.