WYE-354

Chemical Compounds

貨號 Cat. No.
M1755
規格 Size
10mg,50mg
品牌 Brand
No Brand

Description

WYE-354 is a potent and ATP competitive inhibitor of mTOR (IC50 = 5 nM), with significant selectivity over PI3K isofoms (>100-fold). WYE-354 is equally potent against mTORC1 and mTORC2 activities in HEK293 immune complex kinase assays using S6K and Akt as the respective substrate (IC50

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