WP1130
Chemical Compounds
- 貨號 Cat. No.
- M1754
- 規格 Size
- 10mg,50mg,100mg
- 品牌 Brand
- No Brand
Description
WP1130 is a cell-permeable tyrphostin compound that acts as a partially selective deubiquitinase (DUB) inhibitor and suppresses JAK-Stat signaling pathway. Reported to cause accumulation of polyubiquitinated p53, JAK2 and Bcr-Abl, and reduce c-Myc and MCL-1 protein levels in several tumor cells and downregulate Stat3 and NF-κB activities (IC50
