VU 0361737

Chemical Compounds

貨號 Cat. No.
M2576
規格 Size
10mg,50mg
品牌 Brand
No Brand

Description

VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively. VU 0361737 displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.

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