Vitronectin (HV23) Antibody

h1 class=titleVitronectin (HV23) Antibody/h1
div id=node-463 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250265/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pVitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognises fibronectin. This antibody is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin This antibody reacts with vitronectin from cat, dog, goat, cow and to a lesser extent with horse./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/vitronectin-%28hv8%29-antibody250263 Vitronectin (HV8) Antibody/abr /
a href=http://abbiotec.com/antibodies/vitronectin-%28hv2%29-antibody250262 Vitronectin (HV2) Antibody/abr /
a href=http://abbiotec.com/antibodies/vitronectin-%28hv21%29-antibody250264 Vitronectin (HV21) Antibody/abr /
a href=http://abbiotec.com/antibodies/vitronectin-%28a18%29-antibody250266 Vitronectin (A18) Antibody/abr /
a href=http://abbiotec.com/antibodies/vitronectin-%28a27%29-antibody250267 Vitronectin (A27) Antibody/abr /
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h4Alternate Names/h4
pSerum-spreading factor;nbsp; S-protein; V75/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/p04004P04004/abr /
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h4Clonality/h4
pHV23/p
h4Antigen/h4
pnbsp;/p
pHuman vitronectin purified from plasma by heparin-affinity chromatography/p
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h4Application Notes/h4
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pProduct Cat. No. 250265 binds nearly as well to native vitronectin as to denatured. Product Cat. No. 250265 is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding. Product Cat. No. 250265 also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well.nbsp;/p
pE: 1:30,000;/p
pWB: 1:50/p
pstrongReacts with/strongnbsp; :H | Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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