VCH-759
Chemical Compounds
- 貨號 Cat. No.
- M3263
- 規格 Size
- 5mg $140 4-7 Days
- 品牌 Brand
- No Brand
Description
VCH-759 is a non-nucleoside inhibitor of HCV RNA-dependent polymerase with sub-micromolar IC (50) values versus genotype 1a/1b replicons. It was well tolerated and achieved a≥2log10 decline in HCV RNA with 800 mg b.i.d. and t.i.d doses. In a subset of participants, viral rebound was observed and associated with resistant variants. This data supports further evaluation of VCH-759 in combination with interferon–ribavirin treatment.
