Vasoactive Intestinal Peptide Antibody

h1 class=titleVasoactive Intestinal Peptide Antibody/h1
div id=node-434 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250236/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pVasoactive intestinal peptide (VIP) is a 28-amino-acid peptide belonging to the secretin-glucagon family of peptide hormones. Its sequence is identical in man, ox, pig and rat. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in man or peptide histidine-serine (PHI) in pigs or rats, present in the same precursor, and with the neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP). This antibody binds to human, bovine, porcine or rat VIP, but does not bind to PHM or PACAP./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pVIP peptides; Vasoactive intestinal peptide/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P01282P01282/abr /
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h4Clonality/h4
pNA/p
h4Antigen/h4
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pVasoactive intestinal peptide coupled to carrier/p
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h4Application Notes/h4
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pThe dilution guideline of 1:1,000 applies to VIP coated directly at 2 micro;g/mL. For glutaraldehyde-linked VIP-ovalbumin (molar ratio 4:1) coated at 2 micro;g/mL, the dilution is 1:32,000./p
pE: 1:1,000/p
pstrongReacts with/strongnbsp; :H | R | Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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