Vascular Endothelial Growth Factor Receptor-1
- 貨號 Cat. No.
- RCP9016
- 規格 Size
- 10 µg
- 品牌 Brand
- RANDOX-LIFESCIENCES
Description
| Description: | VEGFR-1 belongs to a family of five receptor tyrosine kinase receptors that are specific to a number of angiogenic factors including VEGF and PDGF, and are therefore thought to play a role in the angiogenic process. VEGFR-1 is expressed in two forms, predominantly on endothelial cells, giving rise to a full-length membrane bound receptor and a truncated soluble receptor. Elevated levels of the soluble form of this VEGF receptor may be used in the diagnosis of pathological conditions. RANDOX recombinant VEGFR-1 comprises a 298 amino acid fragment (31-328) corresponding to the IgGlike domains 1-3 from the mature soluble VEGFR protein. VEGF-R1 is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use. |
| Form: | Liquid |
| Purity: | >95% by SDS-PAGE |
| References: | Starovasnik, M. A et al. (1999) J. Mol. Biol. 296 (3) : 531-544. Kanno, S. et al. (2000) Oncogene 19 (17) : 2138-2146. |