Antibodies
UNC669
- 貨號 Cat. No.
- S7373
- 規格 Size
- 10mgã€25mg
- 品牌 Brand
- Selleckchem
Description
UNC669
Catalog No.S7373
UNC669 is a potent and selective MBT (malignant brain tumor) inhibitor with IC50 of 6 μM for L3MBTL1, 5- and 11-fold selective over L3MBTL3 and L3MBTL4.
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
| Description | UNC669 is a potent and selective MBT (malignant brain tumor) inhibitor with IC50 of 6 μM for L3MBTL1, 5- and 11-fold selective over L3MBTL3 and L3MBTL4. | |||||
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| Targets | L3MBTL1 | L3MBTL3 | L3MBTL4 | |||
| IC50 | 6 μM | 35 μM | 69 μM [1] | |||
| In vitro | UNC669, as a low μM binder of L3MBTL1, provides new directions for optimization of MBT inhibitors to improve potency and selectivity. [1] | |||||
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| Features | ||||||
Protocol(Only for Reference)
References
Chemical Information
| Molecular Weight (MW) | 338.24 |
|---|---|
| Formula | C15H20BrN3O |
| CAS No. | 1314241-44-5 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | N/A |
| Solubility (25°C) * | In vitro | DMSO | 11 mg/mL (32 mM) |
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| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 68 mg/mL (201 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Chemical Name | (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone) |
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