Ubiquitin monoclonal

貨號 Cat. No.
AB-001
規格 Size
100 μg
品牌 Brand
Boston Biochem

Description

Ubiquitin monoclonal

Catalog #: AB-001




Ubiquitin monoclonal






Product Source: 

mouse monoclonal



Ubiquitin (U-100H) is a 76 amino acid, highly conserved nuclear and cytoplasmic protein. It is found exclusively in eukaryotes, becomes covalently attached to substrate proteins by enzymes in the Ubiquitin-Proteosome Pathway (UPP) and has a major role in targeting cellular proteins for the ATP-dependent degradation by the 26S proteosome. Ubiquitin becomes covalently linked to itself and/or other proteins either as a single molecule or as poly-ubiquitin chains via a series of ATP-dependent enzymatic steps by E1, E2 and E3 enzymes. Ubiquitination also affects proteasome-independent events such as protein localization, activity and function.


Product Information



Quantity: 

100 μg






Stock: 

100 μg in PBS






Immunogen: 

UBIQ (NP_066289, 1 ~ 76 a.a) full-length human protein with GST (26kD).






Epitope: 

MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG






Isotype: 

IgG1 (Clone 4A1)






Reactivity: 

Human. Other species not tested.




 


Use & Storage



Use: 

Western blot (1:800), ELISA and IP. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.






Storage: 

Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.



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