UBE1L MaxPab polyclonal
- 貨號 Cat. No.
- AB-I30
- 規格 Size
- 50 μl
- 品牌 Brand
- Boston Biochem
Description
UBE1L MaxPab polyclonal
mouse polyclonal
Product Information
50 μl
Use & Storage
Catalog #: AB-I30
UBE1L MaxPab polyclonal
Product Source:
mouse polyclonal
This E1 is responsible for the first step in ISG15-protein isopeptide bond formation. This enzyme catalyzes the activation of the C-terminal carboxyl group of ISG15 by forming a high-energy thioester bond in an ATP-dependent manner. The activated ISG15 is then transferred to UbcH8 and subsequently to lysine groups of target proteins via this thiolester conjugation cascade. The E1 enzyme is a critical component for the initiation of any in vitro conjugation reactions.
Product Information
Quantity:
50 μl
Host:
Mouse
Immunogen:
UBE1L (NP_003326, 1 ~ 1012 a.a) full- length recombinant protein with GST tag.
Epitope:
MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGV
GSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDIT
EDLLLDFQVVVLTAALEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQD
PTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSI
HVREDGSLEIGDTTTFSRYLRGGAITEKRPKTVRHKSLDTALLQPHVVAQSSQEVHH
AHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDE
ALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLQWLYFDALDCLPEDGEL
LPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAG
NSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPTYPLDP
TTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMP
HVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQ
QAHTSADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHF
PPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTA
LRELLKLLPQPDPQQMAPFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLMFE
KDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLEL
YKVVSGPRPRSAFRHSYLHLAENYLIRMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLE
SLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQR
VLVLELSCEGDDEDTAFPPLHYEL
Western Blot Data:
Use & Storage
Use:
Western blotting. Investigator should empirically determine optimal working dilutions. Other applications have not yet been tested.
Storage:
Store at -20oC or -80oC. Aliquot to avoid freeze-thaw cycles.