UbcH2 (E2-14K)

貨號 Cat. No.
E2-607
規格 Size
50 μg 100 μg
品牌 Brand
Boston Biochem

Description

UbcH2 (E2-14K)

Catalog #: E2-607




UbcH2 (E2-14K)






Product Source: 

human recombinant



This E2 enzyme encodes for the human homolog of the yeast Ubc8 gene. UbcH2 can conjugate ubiquitin to histone H2A in an E3-independent manner in vitro. This E2 enzyme is also involved in the ubiquitination of N-end rule pathway substrates, and can function in conjugation with the E3α ligase enzyme. Additionally, UbcH2 may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia. Accession # NP_00335. This protein has an N-terminal GST tag.


Product Information



Quantity: 

50 μg 100 μg






Stock: 

X mg/ml (X μM) in 50 mM HEPES pH 8.0, 100 mM NaCl, 10% glycerol. Actual concentration will vary with specific lot number.






MW: 

17 kDa






Purity: 

> 95% by SDS-PAGE




 


Use & Storage



Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.








Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles



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