UbcH2, Dominant Negative
- 貨號 Cat. No.
- E2-608
- 規格 Size
- 100 μg
- 品牌 Brand
- Boston Biochem
Description
UbcH2, Dominant Negative
human recombinant
Product Information
100 μg
X mg/ml (X μM) in 50 mM HEPES pH 7.8, 50 mM NaCl, 10% glycerol, 1 mM DTT. Actual concentration will vary with specific lot number.
17 kDa
> 95% by SDS-PAGE
Use & Storage
Catalog #: E2-608
UbcH2, Dominant Negative
Product Source:
human recombinant
This E2 enzyme encodes for the human homolog of the yeast Ubc8 gene. UbcH2 can conjugate ubiquitin to histone H2A in an E3-independent manner in vitro. This E2 enzyme is also involved in the ubiquitination of N-end rule pathway substrates, and can function in conjugation with the E3α ligase enzyme. Additionally, UbcH2 may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Product Information
Quantity:
100 μg
Stock:
X mg/ml (X μM) in 50 mM HEPES pH 7.8, 50 mM NaCl, 10% glycerol, 1 mM DTT. Actual concentration will vary with specific lot number.
MW:
17 kDa
Purity:
> 95% by SDS-PAGE
Use & Storage
Use:
Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.
Storage:
Store at -80°C. Avoid multiple freeze/thaw cycles.