U0126

 Alternate Name/Synonyms: 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 109511-58-2

Molecular Formula: C₁₈H₁₆N₆S₂

Molecular Weight: 380.48

Purity: ≥98% by HPLC

Solubility: DMSO (>10 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (ICâ‚…â‚€ values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.

Handling: Protect from air and light