Tubacin

Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. The IC50 for the other HDACs are 1000-fold higher, making tubacin both more selective and more potent than Tubastatin A, which also inhibits HDAC8. Concentration in cell culture experiments typically ranges from 2-50µM.