TSH Receptors Ab

The hyperthyroidism is a disease that produce an
increase in blood circulating levels of thyroid
hormones. In some cases, as in Graves' disease is
caused by autoantibodies against the TSH receptor
(TSHr). Autoantibodies mimic the effect of TSH on
the thyroid gland causing a rise in blood levels of T3
and T4. The determination of these autoantibodies
(TRAb) may be useful for the diagnosis of the disease
and its treatment. The main treatment for Graves’
disease is represented by use of antithyroid drugs
(propylthiouracil or methimazole), I131 and surgery.
The dosage of TRAb is therefore useful in the course
or at the end of therapy.