TrkA, Rabbit Antibody

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Tropomyosin Receptor Kinase; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; neurotrophic receptor tyrosine kinase 1; High Affinity Nerve Growth Factor Receptor; Tyrosine Kinase Receptor A

 

Antibody_Isotype
(Antibody only) : IgGkappa

 

Application_Details :

This antibody binds to human TrkA, a receptor tyrosine kinase involved in the development and the maturation of the CNS and the PNS through regulation of proliferation, differentiation, and survival of the sympathetic and nervous neurons. It is a receptor for NGF and phosphorylates several downstream proteins regulating a variety of signalling cascades. This antibody neutralizes the NGF-TrkA interation.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : MNAC13

 

Datasheet_Link :

 

Description (Long Description) : 

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. This antibody binds to human TrkA, a receptor tyrosine kinase involved in the development and the maturation of the CNS and the PNS through regulation of proliferation, differentiation, and survival of the sympathetic and nervous neurons. It is a receptor for NGF and phosphorylates several downstream proteins regulating a variety of signalling cascades. This antibody neutralizes the NGF-TrkA interation.

 

Expiry_Date : 

12 months after purchase if unopened.

 

Format (Form) : 

Liquid, PBS with 0.02% Proclin 300.

 

Immunogen (Antigen) :Human TrkA ECD.

 

Kit_Components :

 

MSDS (File name) :