TreakR Antibody

Antibody Target: TweakR

Alternative Name: TNFSF12 , TWEAK , MGC20669 , MGC129581 , DR3LG ,

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen: E. coli expressed recombinant human Tweak

Accession#: AAC51923

Gene ID: 8742

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human TWEAKR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Species Reactivity: human

Application: Western blot

Application & Usage: Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually.

Storage Temp.: -20 °C

Shipping: gel pack

Shelf Life: 12 months

Background Descriptions: TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrates that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by biding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in aorta and liver. It may also play a role in vascular cell migration and angiogenesis.

Handling: The antibody solution should be gently mixed before use.