TRAIL Antibody

Antibody Target: TRAIL

Alternative Name: TNFSF10, TRAIL-PEN, TL2, Apo-2L, CD253, APO2L

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen: E. coli expressed recombinant human TRAIL

Accession#: EAW78466

Gene ID: 8743

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified, rabbit anti-TRAIL polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Species Reactivity: human

Application: Western blot, Neutralization

Application & Usage: Western blot analysis (0.5-1 µg/ml), ELISA (2-3 µg/ml) and neutralization (5-10 µg/ml). However, the optimal conditions should be determined individually.

Storage Temp.: -20 °C

Shipping: gel pack

Shelf Life: 12 months

Background Descriptions: TRAIL (TNF-related apoptosis-inducing ligand), a member of the TNF ligand family, is a type II membrane protein and expressed in a variety of human tissues. Two death domains containing receptors DR4 and DR5 have been identified as the receptors for TRAIL and two decoy receptors designated DcR1 and DcR2 inhibit TRAIL function. The multiple receptors suggest a complex role for regulation of signaling by the cytokine. TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

Handling: The antibody solution should be gently mixed before use.