Antibodies
Tolazoline HCl
- 貨號 Cat. No.
- S4124
- 規格 Size
- 50mg
- 品牌 Brand
- Selleckchem
Description
Tolazoline HCl
Catalog No.S4124
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
| Description | Tolazoline is a non-selective competitive α-adrenergic receptor antagonist. | |||||
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| In vitro | Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN). Tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.[1] Tolazoline is not as broadly effective as SNP against all spasmogens investigated. However, it may be effective in counteracting alpha-adrenoceptor-mediated vasospasm in human radial arteries. [2] | |||||
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| Features | ||||||
Protocol(Only for Reference)
References
Chemical Information
| Molecular Weight (MW) | 196.68 |
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| Formula | C10H12N2.HCl |
| CAS No. | 59-97-2 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | N/A |
| Solubility (25°C) * | In vitro | DMSO | 39 mg/mL (198 mM) |
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| Water | 39 mg/mL (198 mM) | ||
| Ethanol | 39 mg/mL (198 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Chemical Name | 1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)-, hydrochloride (1:1) |
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
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| Mass(mg) | 0.19668 | 1.9668 | 3.9336 | 5.9004 |
