TLR3 Antibody

貨號 Cat. No.
3445R-100
規格 Size
100 µg

Description

Antibody Target: TLR3


Host: Rabbit


Antibody Type: Polyclonal


Isotype: Rabbit IgG


Antibody Form: Affinity Purified Antibody


Immunogen: Synthetic peptide surrounding amino acid 805 of mouse TLR3


Accession#: EDL35548


Gene ID: 142980


Appearance: Colorless liquid


Concentration: 0.5 mg/ml


Formulation:


Purification: Affinity purified


Species Reactivity: hu/ms/rt


Application: WB


Application & Usage:


Storage Temp.: -20 °C


Shipping : gel pack


Shelf Life: 12 months


Handling: The antibody solution should be gently mixed before use.


Brief Background Descriptions: To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.

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