Tissue Inhibitor of Metalloproteinase 1
- 貨號 Cat. No.
- RCP9170
- 規格 Size
- 10 µg
- 品牌 Brand
- RANDOX-LIFESCIENCES
Description
| Description: | TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the N-terminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells. RANDOX recombinant TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the mature TIMP-1 protein and is expressed in E. coli with an aminoterminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use. |
| Form: | Liquid |
| Purity: | >95% by SDS-PAGE |
| References: | Docherty AJ. et al., (1985) Nature. 318: 66-69. |