Kits
Thyreoglobulin (human) (hTG), ELISA
- 貨號 Cat. No.
- K 7510
- 規格 Size
- 96 Tests
- 品牌 Brand
- IDS
Description
| Article number: | K 7510 |
| Method: | ELISA |
| Tests: | 96 Tests |
| Matrix: | Plasma, Serum |
| Volume: | 100 µl |
| Incubation time: | 3h; 1h; 15min |
| Standards: | 4-250 µg/l |
| Human Thyreoglobulin (hTG) is a large glycoprotein (MW 650.000) that is stored in the follicular colloid of the thyroid gland. It functions as a prohormone in the intrathyroid synthesis of T3 and T4. Traditionally circulating levels of hTG have been measured using double antibody immunoassays. HTG is evaluated in thyroid follicular and papillary carcinoma, thyroid adenoma, subacute thyroiditis, Hashimoto´s thyroiditis and Grave´s disease; hTG levels are not increased in patients with medullary thyroid carcinoma. Measurement of hTG is most useful in detecting recurrence of differentiated thyroid carcinoma following surgical resection or radioactive iodine ablation. HTG determination is used as an adjunct to iodine 131 scanning but not as a replacement for it. Assessment of serum hTG also aids in the management of infants with congenital hypothyroidism. Low levels of hTG are an indication that thyrotoxicosis factitia may be present. |