Thrombospondin I (A65M) Antibody

h1 class=titleThrombospondin I (A65M) Antibody/h1
div id=node-459 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250261/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pThrombospondin 1 (TSP1) is a multidomain, multifunctional glycoprotein from platelets and certain vascular cells which has been shown to play an important role in cell-cell and cell-matrix interactions. TSP1 is a calcium-sensitive, disulfide-bonded trimer with a subunit molecular mass of 150 kDa. TSP1 exists in different conformational states depending on the calcium ion concentration used in the purification buffers. This antibody is highly specific for the low-calcium conformation (0.1 mmol/l) of human TSP1. There is no evidence of cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin). Cross-reactivity with thrombospondins from other species has not been tested./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pThrombospondin-1; THBS1; TSP; TSP1/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P07996P07996/abr /
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h4Clonality/h4
pA65M/p
h4Antigen/h4
pnbsp;/p
pExtracellular matrix material from cultured bovine corneal endothelial cells/p
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h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250261 can be used for immunoprecipitation and for immunostaining of frozen periodate-lysine-paraformaldehyde-fixed sections of bovine and human tissues. Product Cat. No. 250261 can also be used to probe for the low-calcium conformation of thrombospondin./p
pE: 1:200;/p
pIHC: 1:40/p
pIP:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H | Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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