Thrombin (5D10) Antibody

h1 class=titleThrombin (5D10) Antibody/h1
div id=node-540 class=node ntype-antibodiesMouse Monoclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250340/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
h4
pnbsp;/p
Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Description/h4
pThrombin is the active enzyme that splits fibrinogen into fibrin in final stage of blood coagulation. It is generated from its circulating inactive precursor, prothrombin, by the action of factor Xa aided by factor Va, phospholipid and calcium ions. Thrombin is a glycoprotein formed by a 6-kDa A chain linked by a disulfide bridge to a 31-kDa B chain which carries the serine protease catalytic site. This antibody binds to human thrombin and to complexes of human thrombin with the thrombin inhibitor hirudin. No cross-reaction is seen with prothrombin. Cross-reactivity with thrombin from other species has not been tested./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/acetylcholinesterase-%2812b4%29-antibody250341 Thrombin (5G9) Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pCoagulation factor II/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P00734P00734/abr /
nbsp;/p
h4Clonality/h4
p5D10/p
h4Antigen/h4
pnbsp;/p
pThrombin isolated from activated human plasma and adsorbed onto aluminum hydroxide gel/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250340 binds to human thrombin and to complex of human thrombin with the thrombin inhibitor hirudin. No cross-reaction is seen with prothrombin. Cross-reactivity with thrombin from other species has not been tested. The antigenicity of thrombin is lost by biotinylation./p
pE: 1:50/p
pWB: 1:50/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div