Kits
Thiol-Status (Sulfhydryl-Status Test), colorimetric
- 貨號 Cat. No.
- K 1800
- 規格 Size
- 96 Tests
- 品牌 Brand
- IDS
Description
| Article number: | K 1800 |
| Method: | colorimetric |
| Tests: | 96 Tests |
| Matrix: | Serum, Plasma, Urine, Synovia |
| Volume: | 20 µl |
| Incubation time: | 30 min |
| Standards: | one point calibration |
| Serum protein thiol levels in blood are a direct measure of the in vivo reduction/oxidation (redox) status in humans, because thiols react readily with oxygen-containing free radicals to form disulfides. Moreover, serum thiols also reflect DNA repair capacity and the possible eventual accumulation of genetic damage, since a key DNA repair enzyme, poly ADP-ribose polymerase (PARP), is thiol/disulfide redox regulated. Serum protein thiols can possibly be used to estimate individual aging status. Data from Banne AF et al. (2003, Anti Aging Med 6:327-34) strongly confirm an important role of oxidative stress in human disease development, and identify serum thiol status as a potential biochemical endpoint useful in the assessment of aging. |