TGF-beta Receptor II Antibody

Antibody Target: TGF-b Receptor II

Host: Goat

Antibody Type: Polyclonal

Isotype: Goat IgG

Antibody Form: Affinity Purified Antibody

Immunogen: Recombinant human TGF-b RII

Accession#: P37173

Gene ID: 7048

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) antigen affinity purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide.

Purification: Affinity purified

Species Reactivity: hu

Application: WB/IHC

Application & Usage: Western blotting (0.5-1 µg/ml), immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes human TGF-β Receptor II. Reactivity to other species has not been tested.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: TGF-β (Transforming growth factor-beta superfamily members are critical regulators of cell proliferation, differentiation, morphogenesis, and pathogenesis. TGF-beta receptor is a serine/threonine kinase receptor complex that consists of two distinct transmembrane proteins known as type I and type II receptors. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and thus activation of the type I receptor kinases.