TGF-beta 1 Antibody

h1 class=titleTGF-beta 1 Antibody/h1
div id=node-1654 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250876/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe TGF-beta superfamily is composed of numerous growth differentiation factors, including transforming growth factor beta 1, 2 , and 3 (TGF-beta 1, TGF-beta 2 and, TGF-beta 3). TGF-beta 1 controls proliferation, differentiation and other functions in many cell types. TGF-beta 1 is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. The inactive form consists of a TGF-beta 1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The active form is a disulfide-linked homodimer of mature TGF-beta 1. Defects in TGF-beta 1 are the cause of Camurati-Emgelmann disease, a progressive diaphyseal dysplasia characterized by hyperostosis ans sclerosis of the diaphyses of long bones./p
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h4Recommended Products/h4
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h4Alternate Names/h4
pTransforming growth factor beta-1; TGF-beta-1; TGFB1; TGFB; Latency-associated peptide; LAP/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P01137P01137/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGF-beta 1./p
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h4Application Notes/h4
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pCat. No. 250876 does not react with TGF-beta 2 and TGF-beta 3./p
pE: 1:500-1:1,000/p
pWB: 1:100-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H | M | R/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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