TFF-2/Spasmolysin Antibody

Antibody Target: TFF-2

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen: E. coli expressed human TFF-2

Accession#: Q03403

Gene ID: 7032

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-human TFF-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Species Reactivity: hu

Application: WB

Application & Usage: Western blot analysis (0.5-2 µg/ml). Per researchers feedback, it can also be used in ELISA (2-3 µg/ml) and neutralization (3-6 µg/ml). However, the optimal conditions should be determined individually.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma. Human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues.