Tetranectin (5B7) Antibody

h1 class=titleTetranectin (5B7) Antibody/h1
div id=node-550 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250350/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pTetranectin (TN) is a serum and tissue protein, a C-type lectin, which binds to Ca++. It is a homotrimer of monomers each with a mass of 20 kDa, plasma or serum concentrations of TN are found to be approximately 10 mg/l. In vitro, TN can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. TN is best known as a prognostic marker in ovarian cancer. This antibody is specific for amino acids 17-181 of human tetranectin monomer./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/tetranectin-%286f9%29-antibody250352 Tetranectin (6F9) Antibody/abr /
a href=http://abbiotec.com/antibodies/tetranectin-%2810e3%29-antibody250351 Tetranectin (10E3) Antibody/abr /
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h4Alternate Names/h4
pTN;nbsp; C-type lectin domain family 3 member B;nbsp; Plasminogen kringle 4-binding protein/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P05452P05452/abr /
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h4Clonality/h4
p5B7/p
h4Antigen/h4
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pTetranectin purified from human citrate plasma (3) and coupled to PPD.nbsp; Boosted before fusion with recombinant tetranectin produced in E. coli./p
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h4Application Notes/h4
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pProduct Cat. No. 250350 reacts strongly with TN monomer in western blot. Product Cat. No. 250350 is used as detection antibody in combination with Product Cat. No. 250352 in sandwich ELISA, but reacts poorly in sandwich ELISA in combination with a polyclonal antibody against tetranectin. The antibody gives a strong signal for TN in immunohistochemistry on both fresh frozen and paraffin-embedded tissues./p
pE: 1:25/p
pWB: 1:100/p
pIHC: 1:40/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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