Kits
Testosterone ELISA
Kits
Description
Testosterone (17β-OH-4-androstene-3-one) is a
steroid hormone family of androgens mainly
produced by the Leydig cells located in the testes
and, minimally, by the ovaries and the adrenal cortex.
It is also present in women who, compared to men,
have a greater tendency to convert into estrogen this
hormone.
In postpubertal males, testosterone is secreted
primarily by the testes with only a small amount
derived from peripheral conversion of
androstenedione. In humans is deputy to the
development of the sexual organs (differentiation of
the testis and the whole genital apparatus) and of
secondary sexual characteristics, such as beard, hair
distribution, the timbre of the voice and muscles. The
testosterone, during puberty, is also involved on
skeletal development, limiting the elongation of the
long bones and avoiding, in this way, a
disproportionate growth of the limbs. In adult humans,
the levels of testosterone have a very important role
as regards the sexuality, the musculoskeletal system,
the vitality and good health (mainly understood as
protection from metabolic diseases such as
hypertension and diabetes mellitus); helps to ensure
fertility, as it stimulates the maturation of sperm in the
testes. Also influence the quality and quantity of
sperm produced, since the seminal work on the
streets and on the prostate, deputies to the
production of sperm. Daily production of testosterone
in men varies from 5 to 7 milligrams, but exceeded 30
years, tends to decrease annually by 1%. In adult
women over 50% of serum testosterone is derived
from peripheral conversion of androstenedione
secreted by the adrenal and ovary, with the remainder
from direct secretion of testosterone by these glands.
The majority of circulating testosterone is bound by
SHBG and a smaller portion is bound by albumin.
Only a small percentage ( 1%) exists in circulation
as unbound or free testosterone.
Testosterone effects can be classified as virilizing
and anabolic effects, although the distinction is
somewhat artificial, as many of the effects can be
considered both. Anabolic effects include growth of
muscle mass and strength, increased bone density
and strength, and stimulation of linear growth and
bone maturation. Virilizing effects include maturation
of the sex organs, and after birth (usually at puberty)
a deepening of the voice, growth of the beard and
axillary hair (male secondary sex characteristics).
Testosterone levels decline gradually with age in men
(andropause). The signs and symptoms are nonspecific,
and are generally associated with aging such
as loss of muscle mass and bone density, decreased
physical endurance, decreased memory ability and
loss of libido.
In females of all ages, elevated testosterone levels
can be associated with a variety of virilizing
conditions, including adrenal tumors and polycystic
ovarian disease.
steroid hormone family of androgens mainly
produced by the Leydig cells located in the testes
and, minimally, by the ovaries and the adrenal cortex.
It is also present in women who, compared to men,
have a greater tendency to convert into estrogen this
hormone.
In postpubertal males, testosterone is secreted
primarily by the testes with only a small amount
derived from peripheral conversion of
androstenedione. In humans is deputy to the
development of the sexual organs (differentiation of
the testis and the whole genital apparatus) and of
secondary sexual characteristics, such as beard, hair
distribution, the timbre of the voice and muscles. The
testosterone, during puberty, is also involved on
skeletal development, limiting the elongation of the
long bones and avoiding, in this way, a
disproportionate growth of the limbs. In adult humans,
the levels of testosterone have a very important role
as regards the sexuality, the musculoskeletal system,
the vitality and good health (mainly understood as
protection from metabolic diseases such as
hypertension and diabetes mellitus); helps to ensure
fertility, as it stimulates the maturation of sperm in the
testes. Also influence the quality and quantity of
sperm produced, since the seminal work on the
streets and on the prostate, deputies to the
production of sperm. Daily production of testosterone
in men varies from 5 to 7 milligrams, but exceeded 30
years, tends to decrease annually by 1%. In adult
women over 50% of serum testosterone is derived
from peripheral conversion of androstenedione
secreted by the adrenal and ovary, with the remainder
from direct secretion of testosterone by these glands.
The majority of circulating testosterone is bound by
SHBG and a smaller portion is bound by albumin.
Only a small percentage ( 1%) exists in circulation
as unbound or free testosterone.
Testosterone effects can be classified as virilizing
and anabolic effects, although the distinction is
somewhat artificial, as many of the effects can be
considered both. Anabolic effects include growth of
muscle mass and strength, increased bone density
and strength, and stimulation of linear growth and
bone maturation. Virilizing effects include maturation
of the sex organs, and after birth (usually at puberty)
a deepening of the voice, growth of the beard and
axillary hair (male secondary sex characteristics).
Testosterone levels decline gradually with age in men
(andropause). The signs and symptoms are nonspecific,
and are generally associated with aging such
as loss of muscle mass and bone density, decreased
physical endurance, decreased memory ability and
loss of libido.
In females of all ages, elevated testosterone levels
can be associated with a variety of virilizing
conditions, including adrenal tumors and polycystic
ovarian disease.