TCS PIM-1 1
Chemical Compounds
- 貨號 Cat. No.
- M3745
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
TCS PIM-1 1 is a potent, ATP-competitive inhibitor of Pim-1 kinase. This compound displays selectivity over Pim-2 and MEK1/MEK2 (IC50 values are 50, >20000 and >20000 nM for Pim-1, Pim-2, and MEK1/MEK2, respectively). TCS PIM-1 1 bound convincingly within the ATP-binding site of Pim-1 suggesting an ATP-competitive inhibitory mechanism.
