Surfactant protein D (10B2) Antibody

h1 class=titleSurfactant protein D (10B2) Antibody/h1
div id=node-603 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250403/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pSurfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is approximately 700 ng/ml in healthy individuals. This antibody is specific for SP-D from amniotic fluid, serum and bronchioalveolar lavage. The antibody blocks SP-D binding to GP-340 but not to carbohydrates./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/surfactant-protein-d-%2816c11%29-antibody250402 Surfactant protein D (16C11) Antibody/abr /
a href=http://abbiotec.com/antibodies/surfactant-protein-d-%2812g5%29-antibody250401 Surfactant protein D (12G5) Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pPulmonary surfactant-associated protein D;nbsp; SP-D;nbsp; PSP-D;nbsp; PSPD;nbsp; Lung surfactant protein D/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P35247P35247/abr /
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h4Clonality/h4
p10B2/p
h4Antigen/h4
pnbsp;/p
pNative human SP-D purified from late pregnancy amniotic fluid/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250403 is used as detection antibody in sandwich ELISAwith a polyclonal antibody. Antibody binding is calcium-dependent. Product Cat. No. 250403 only reacts in western blot with non-reduced SP-D./p
pE: 1:2,000/p
pWB: 1:2,000/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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