SUMO-2 K11R mutant
- 貨號 Cat. No.
- ULM-752
- 規格 Size
- 250 μg
- 品牌 Brand
- Boston Biochem
Description
SUMO-2 K11R mutant
human recombinant
Product Information
250 μg
X mg/ml (XμM) in 50 mM HEPES pH 8.0, 150 mM NaCl, 1mM DTT. Actual concentration varies with lot number.
10.6 kDa
> 95% by SDS-PAGE
Use & Storage
Store at -80°C once reconstituted. Avoid multiple freeze/thaw cycles.
Catalog #: ULM-752
SUMO-2 K11R mutant
Product Source:
human recombinant
Mutation of lysine 11 to arginine renders SUMO-2 unable to form poly-SUMO multimers and is useful to investigate mono-SUMOylation or can be used to reduce poly-SUMO chain formation. Human SUMO-2 contains the VK11TE sequence which allows for the formation of poly-SUMO chains. K11 is the conserved lysine that becomes modified and is the point of attachment for the C-terminal glycine of the preceding SUMO-2. The function of SUMO chains has not yet been fully elucidated.
Product Information
Quantity:
250 μg
Stock:
X mg/ml (XμM) in 50 mM HEPES pH 8.0, 150 mM NaCl, 1mM DTT. Actual concentration varies with lot number.
MW:
10.6 kDa
Purity:
> 95% by SDS-PAGE
Use & Storage
Use:
Typical in vitro concentrations for conjugate formation is 10-50 μM depending on conditions.
Storage:
Store at -80°C once reconstituted. Avoid multiple freeze/thaw cycles.