STK11 (4H12) Antibody

STK11 (Serine/threonine-protein kinase 11) is a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Defects in STK11 are a cause of predisposition to benign and maligant tumors including gastrointestinal and testicular cancers (Peutz-Jeghers syndrome).